Probabilistic Study on Subunit Mismatch Arrangement in Staphylococcal γ-hemolysin Heteroheptameric Transmembrane Pore

Probabilistic Study on Subunit Mismatch Arrangement in Staphylococcal γ-hemolysin Heteroheptameric Transmembrane Pore

Staphylococcal γ-hemolysin (Hlg), consists of two separate proteins, Hlg1 (LukF) of 34 kDa and Hlg2 of 32 kDa, which cooperatively lyse mammalian erythrocytes. Hlg is an illustrative molecule for the study of the assembly and membrane insertion of transmembrane proteins having the unique c...

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Bibliographic Details
Main Authors: Noriko TOMITA, Kazuyo ABE, Jun KANEKO, Yoshiyuki KAMIO, Makoto OHTA
Format: Article
Language:English
Published: The Japan Society of Mechanical Engineers 2011-10-01
Series:Journal of Biomechanical Science and Engineering
Subjects:
staphylococcal γ-hemolysin
two-component hemolysin
pore-forming toxin
heteroheptamer
transmission electron microscopy
probabilistic analysis
subunit mismatch arrangement
Online Access:https://www.jstage.jst.go.jp/article/jbse/6/4/6_4_286/_pdf/-char/en

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https://www.jstage.jst.go.jp/article/jbse/6/4/6_4_286/_pdf/-char/en

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