Urine-derived cells from the aged donor for the 2D/3D modeling of neural cells via iPSCs

Urine-derived cells from the aged donor for the 2D/3D modeling of neural cells via iPSCs

Human neural cell models derived from induced pluripotent stem cells (iPSCs) have been widely accepted to model various neurodegenerative diseases such as Alzheimer’s disease (AD) in vitro. Although the most common sources of iPSCs are fibroblasts and peripheral blood mononuclear cells, the collecti...

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Bibliographic Details
Main Authors: Sopak Supakul, Yuki Hatakeyama, Nicolas Leventoux, Maika Itsuno, Naoko Numata, Hayato Hiramine, Satoru Morimoto, Atsushi Iwata, Sumihiro Maeda, Hideyuki Okano
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Aging Brain
Subjects:
Urine
Induced pluripotent stem cell (iPSC)
Disease modeling
Neurons
Cortical brain organoids
Astrocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S2589958923000385

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http://www.sciencedirect.com/science/article/pii/S2589958923000385

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