Synergistic effect of IFN-γ and IL-1β on PD-L1 expression in hepatocellular carcinoma

Synergistic effect of IFN-γ and IL-1β on PD-L1 expression in hepatocellular carcinoma

Immunotherapy using anti-programmed death 1 ligand 1 (PD-L1) antibodies has shown clinical efficacy against hepatocellular carcinoma (HCC) and is recognized as the first-line treatment for unresectable HCC. PD-L1 expression is affected by various cytokines produced by immune cells in the tumor micro...

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Bibliographic Details
Main Authors: Yasunao Numata, Noriyuki Akutsu, Keisuke Ishigami, Hideyuki Koide, Kohei Wagatsuma, Masayo Motoya, Shigeru Sasaki, Hiroshi Nakase
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Synergistic effect
PD-L1
IFN-γ
IL-1β
Hepatocellular carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S240558082200070X

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http://www.sciencedirect.com/science/article/pii/S240558082200070X

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