Electrochemical Radical Tandem Difluoroethylation/Cyclization of Unsaturated Amides to Access MeCF<sub>2</sub>-Featured Indolo/Benzoimidazo [2,1-<i>a</i>]Isoquinolin-6(5<i>H</i>)-ones

Electrochemical Radical Tandem Difluoroethylation/Cyclization of Unsaturated Amides to Access MeCF<sub>2</sub>-Featured Indolo/Benzoimidazo [2,1-<i>a</i>]Isoquinolin-6(5<i>H</i>)-ones

A metal-free electrochemical oxidative difluoroethylation of 2-arylbenzimidazoles was accomplished, which provided an efficient strategy for the synthesis of MeCF<sub>2</sub>-containing benzo[4,5]imidazo[2,1-<i>a</i>]-isoquinolin-6(5<i>H</i>)-ones. In addition, th...

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Bibliographic Details
Main Authors: Yunfei Tian, Dongyu Guo, Luping Zheng, Shaolu Yang, Ningning Zhang, Weijun Fu, Zejiang Li
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molecules
Subjects:
electrochemical synthesis
difluoroethylation
radical
polycyclic compounds
tandem cyclization
Online Access:https://www.mdpi.com/1420-3049/29/5/973

Internet

https://www.mdpi.com/1420-3049/29/5/973

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