Quantitative behavioural phenotyping to investigate anaesthesia induced neurobehavioural impairment

Abstract Anaesthesia exposure to the developing nervous system causes neuroapoptosis and behavioural impairment in vertebrate models. Mechanistic understanding is limited, and target-based approaches are challenging. High-throughput methods may be an important parallel approach to drug-discovery and...

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Bibliographic Details
Main Authors: Pratheeban Nambyiah, Andre E. X. Brown
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98405-x