CDC42 governs normal oviduct multiciliogenesis through activating AKT to ensure timely embryo transport

Abstract Ciliated and secretory cells are two major cell types that comprise the oviduct epithelia. Accumulating evidences support a role of oviductal multiciliated epithelia for embryo transport, however the mechanisms underlying this specialized cell type differentiation remain elusive. Here, we r...

Full description

Bibliographic Details
Main Authors: Ruiwei Jiang, Xiaofang Tang, Jiale Pan, Gaizhen Li, Ningjie Yang, Yedong Tang, Shilei Bi, Han Cai, Qionghua Chen, Dunjin Chen, Haibin Wang, Shuangbo Kong
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05184-y