All-trans retinoic acid enhances the anti-tumour effects of fimaporfin-based photodynamic therapy

All-trans retinoic acid enhances the anti-tumour effects of fimaporfin-based photodynamic therapy

The vitamin A metabolite all-trans retinoic acid (ATRA; tretinoin) has anticancer potential. However, lack of clinical success has prevented its approval for solid tumours. Herein, we propose combining short-term low-dose ATRA with fimaporfin-based photodynamic therapy (ATRA+PDT) for the improved tr...

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Bibliographic Details
Main Authors: Judith Jing Wen Wong, Susanne Lorenz, Pål Kristian Selbo
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
ATRA
Carcinoma
Photodynamic therapy
Apoptosis
Unfolded protein response
Experimental cancer therapeutics
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222010678

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http://www.sciencedirect.com/science/article/pii/S0753332222010678

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