Dopamine enhances recovery after traumatic brain injury through ubiquitylation and autophagic degradation of RIPK1

Abstract Background Although the neurotransmitter dopamine (DA) plays a crucial pathophysiologic role after traumatic brain injury (TBI), its function and specific underlying mechanisms of action remain unclear. Methods Adult male mice underwent controlled cortical impact (CCI). We administered DA i...

Full description

Bibliographic Details
Main Authors: Hui Luo, Ning Liu, Chao Lin
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-024-01515-y