Expression, purification and biological characterisation of recombinant human irisin (12.5 kDa)

Fibronectin type III domain containing 5 (FNDC5) is a transmembrane protein. Upon cleavage, it yields a peptide called irisin that is supposedly bind to an unknown receptor and facilitates browning of white adipose tissue (WAT). Increased levels of irisin are associated with increased levels of ener...

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Bibliographic Details
Main Authors: Kalpana Panati, Venkata Ramireddy Narala, Vydyanath R. Narasimha, Madhavi Derangula, Venkat R.R. Arva Tatireddigari, Suneetha Yeguvapalli
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Journal of Genetic Engineering and Biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S1687157X18300672