M1- and M2-type macrophage responses are predictive of adverse outcomes in human atherosclerosis

Atherosclerosis is an inflammatory disease caused by endothelial injury, lipid deposition and oxidative stress. This progressive disease can be converted into an acute clinical event by plaque rupture and thrombosis. In the context of atherosclerosis, the underlying cause of myocardial infarction an...

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Bibliographic Details
Main Authors: Monica De Gaetano, Daniel Crean, Mary Barry, Orina Belton
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00275/full