Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke

Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke

Nitrones are encouraging drug candidates for the treatment of oxidative stress-driven diseases such as acute ischemic stroke (AIS). In a previous study, we found a promising quinolylnitrone, QN23, which exerted a neuroprotective effect in neuronal cell cultures subjected to oxygen–glucose deprivatio...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Emma Martínez-Alonso, Alejandro Escobar-Peso, Alicia Aliena-Valero, Germán Torregrosa, Mourad Chioua, Rocío Fernández-Serra, Daniel González-Nieto, Youness Ouahid, Juan B. Salom, Jaime Masjuan, José Marco-Contelles, Alberto Alcázar
Formaat: Artikel
Taal:English
Gepubliceerd in: MDPI AG 2022-06-01
Reeks:Antioxidants
Onderwerpen:
antioxidants
brain ischemia
ischemic stroke
neuroprotection
quinolyl nitrones
pharmacokinetics
Online toegang:https://www.mdpi.com/2076-3921/11/6/1186

Internet

https://www.mdpi.com/2076-3921/11/6/1186

Gelijkaardige items