Potential senotherapeutic candidates and their combinations derived from transcriptional connectivity and network measures

Cellular senescence, a state of permanent cell cycle arrest, is associated with organismal aging and malfunctioning. Various attempts have been made to find a unified gene signature for all senescence models in every cell type. However, with more studies being conducted, none look to be universally...

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Bibliographic Details
Main Authors: Amirhossein Nayeri Rad, Golnaz Shams, Roberto A. Avelar, Mohammad Hossein Morowvat, Younes Ghasemi
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914822000697