Sex Differences in Opioid Response Linked to <i>OPRM1</i> and <i>COMT</i> genes DNA Methylation/Genotypes Changes in Patients with Chronic Pain

Sex Differences in Opioid Response Linked to <i>OPRM1</i> and <i>COMT</i> genes DNA Methylation/Genotypes Changes in Patients with Chronic Pain

Analgesic-response variability in chronic noncancer pain (CNCP) has been reported due to several biological and environmental factors. This study was undertaken to explore sex differences linked to <i>OPRM1</i> and <i>COMT</i> DNA methylation changes and genetic variants in a...

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Bibliographic Details
Main Authors: Laura Agulló, Javier Muriel, César Margarit, Mónica Escorial, Diana Garcia, María José Herrero, David Hervás, Juan Sandoval, Ana M. Peiró
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Clinical Medicine
Subjects:
sex differences
chronic pain
epigenetics
DNA methylation
pharmacogenetics
Online Access:https://www.mdpi.com/2077-0383/12/10/3449

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https://www.mdpi.com/2077-0383/12/10/3449

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