Methicillin resistance alters the biofilm phenotype and attenuates virulence in Staphylococcus aureus device-associated infections.

Clinical isolates of Staphylococcus aureus can express biofilm phenotypes promoted by the major cell wall autolysin and the fibronectin-binding proteins or the icaADBC-encoded polysaccharide intercellular adhesin/poly-N-acetylglucosamine (PIA/PNAG). Biofilm production in methicillin-susceptible S. a...

Full description

Bibliographic Details
Main Authors: Clarissa Pozzi, Elaine M Waters, Justine K Rudkin, Carolyn R Schaeffer, Amanda J Lohan, Pin Tong, Brendan J Loftus, Gerald B Pier, Paul D Fey, Ruth C Massey, James P O'Gara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22496652/?tool=EBI