Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae.

Metabolite concentrations can regulate gene expression, which can in turn regulate metabolic activity. The extent to which functionally related transcripts and metabolites show similar patterns of concentration changes, however, remains unestablished. We measure and analyze the metabolomic and trans...

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Bibliographic Details
Main Authors: Patrick H Bradley, Matthew J Brauer, Joshua D Rabinowitz, Olga G Troyanskaya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2614473?pdf=render