A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses.

A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses.

Understanding the mechanisms by which pathogens induce vascular inflammation and dysfunction may reveal novel therapeutic targets in sepsis and related conditions. The intracellular receptor NOD1 recognises peptidoglycan which features in the cell wall of gram negative and some gram positive bacteri...

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Bibliographic Details
Main Authors: Timothy Gatheral, Daniel M Reed, Laura Moreno, Peter J Gough, Bart J Votta, Clark A Sehon, David J Rickard, John Bertin, Eric Lim, Andrew G Nicholson, Jane A Mitchell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3411636?pdf=render

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http://europepmc.org/articles/PMC3411636?pdf=render

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