Does prenatal valproate interact with a genetic reduction in the serotonin transporter?A rat study on anxiety and cognition

There is ample evidence that prenatal exposure to valproate (or valproic acid, VPA) enhances the risk of developing Autism Spectrum Disorders (ASD). In line with this, a single injection of VPA induces a multitude of ASD-like symptoms in animals such as rats and mice. However, there is equally stron...

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Bibliographic Details
Main Authors: Bart A Ellenbroek, Caren August, Jiun Youn
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00424/full