Exon Skipping in a Dysf-Missense Mutant Mouse Model
Limb girdle muscular dystrophy 2B (LGMD2B) is without treatment and caused by mutations in the dysferlin gene (DYSF). One-third is missense mutations leading to dysferlin aggregation and amyloid formation, in addition to defects in sarcolemmal repair and progressive muscle wasting. Dysferlin-null mo...
| প্রধান লেখক: | , , , , , , , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
Elsevier
2018-12-01
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| মালা: | Molecular Therapy: Nucleic Acids |
| অনলাইন ব্যবহার করুন: | http://www.sciencedirect.com/science/article/pii/S2162253118302257 |