Neuroprotective effects of metformin on cerebral ischemia‐reperfusion injury by regulating PI3K/Akt pathway

Abstract Metformin (Met) is a commonly used drug in the treatment of type 2 diabetes. Currently, it has been found that Met can effectively reduce the incidence of stroke and exert anti‐inflammatory effects. However, its role in ischemia‐reperfusion (I/R)‐induced nerve injury remains unclear. This s...

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Bibliographic Details
Main Authors: Cailian Ruan, Hongtao Guo, Jiaqi Gao, Yiwei Wang, Zhiyong Liu, Jinyi Yan, Xiaoji Li, Haixia Lv
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Brain and Behavior
Subjects:
Online Access:https://doi.org/10.1002/brb3.2335