Comparison of the In Vitro and Ex Vivo Permeation of Existing Topical Formulations Used in the Treatment of Facial Angiofibroma and Characterization of the Variations Observed

Rapamycin has been used topically to treat facial angiofibromas associated with tuberous sclerosis for more than a decade. In the absence of a commercial form, a large number of formulations have been clinically tested. However, given the great heterogeneity of these studies, particularly with regar...

Full description

Bibliographic Details
Main Authors: Guillaume Le Guyader, Bernard Do, Victoire Vieillard, Karine Andrieux, Muriel Paul
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/11/1060