In Vitro Stimulation of Multidrug Resistance-Associated Protein 2 Function Is Not Reproduced In Vivo in Rats
Previously we reported that coproporphyrin-I (CP-I) is an optimal probe substrate for multidrug resistance-associated protein 2 (MRP2), and stimulation of MRP2-mediated transport is probe substrate-dependent. In the present investigation, we assessed if the in vitro stimulation is physiologically re...
Main Authors: | Ravindranath Reddy Gilibili, Vishwanath Kurawattimath, Bokka Venkata Murali, Yurong Lai, T. Thanga Mariappan, Hong Shen, Sagnik Chatterjee |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-08-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4923/10/3/125 |
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