Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death

<p>Abstract</p> <p>Background</p> <p>Glycogen Synthase Kinase-3 (GSK-3) α and β are two serine-threonine kinases controlling insulin, Wnt/β-catenin, NF-κB signaling and other cancer-associated transduction pathways. Recent evidence suggests that GSK-3 could function as...

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Main Authors: Colpo Anna, Pavan Laura, Montini Barbara, Tubi Laura, Manni Sabrina, Piazza Francesco, Gnoato Marianna, Cabrelle Anna, Adami Fausto, Zambello Renato, Trentin Livio, Gurrieri Carmela, Semenzato Gianpietro
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/526