Activation of p53 After Irradiation Impairs the Regenerative Capacity of the Mouse Liver

Activation of p53 After Irradiation Impairs the Regenerative Capacity of the Mouse Liver

Radiation therapy is one of the treatment methods for hepatocellular carcinoma. However, radiation tolerance of the liver is low, and the detailed effect of radiation on liver regeneration has not been clarified. C57BL/6J mice or hepatocyte‐specific p53 knockout (KO) mice (albumin [Alb]‐Cre Trp53flo...

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Bibliographic Details
Main Authors: Makiko Urabe, Hayato Hikita, Yoshinobu Saito, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuta Myojin, Akira Doi, Katsuhiko Sato, Sadatsugu Sakane, Yuki Makino, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2022-02-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1815

Internet

https://doi.org/10.1002/hep4.1815

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