Complement factor H Y402H polymorphism results in diminishing CD4+ T cells and increasing C-reactive protein in plasma

Abstract Age-related macular degeneration (AMD) is a common cause of visual loss among the elderly. Genetic variants in the gene encoding complement factor H (CFH) have been identified as an AMD susceptibility gene, however, the mechanistic link is debated. Here, we investigated the link between the...

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Bibliographic Details
Main Authors: Marie Krogh Nielsen, Yousif Subhi, Mads Falk, Amardeep Singh, Torben Lykke Sørensen, Mogens Holst Nissen, Carsten Faber
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46827-0