Sorafenib Alleviates Inflammatory Signaling of Tumor Microenvironment in Precancerous Lung Injuries

Sorafenib Alleviates Inflammatory Signaling of Tumor Microenvironment in Precancerous Lung Injuries

According to population-based studies, lung cancer is the prominent reason for cancer-related mortality worldwide in males and is also rising in females at an alarming rate. Sorafenib (SOR), which is approved for the treatment of hepatocellular carcinoma and renal cell carcinoma, is a multitargeted...

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Bibliographic Details
Main Authors: Betul Cicek, Ahmet Hacimuftuoglu, Mehmet Kuzucu, Ahmet Cetin, Yesim Yeni, Sidika Genc, Serkan Yildirim, Ismail Bolat, Mecit Kantarci, Mustafa Gul, Serhat Hayme, Dimitris Matthaios, Dimitra P. Vageli, Sotirios G. Doukas, Aristidis Tsatsakis, Ali Taghizadehghalehjoughi
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceuticals
Subjects:
lung carcinogenesis
diethylnitrosamine
inflammation
SOX-2
COX-2
JNK
Online Access:https://www.mdpi.com/1424-8247/16/2/221

Internet

https://www.mdpi.com/1424-8247/16/2/221

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