Molecular, Subcellular, and Arrhythmogenic Mechanisms in Genetic RyR2 Disease
The ryanodine receptor (RyR2) has a critical role in controlling Ca<sup>2+</sup> release from the sarcoplasmic reticulum (SR) throughout the cardiac cycle. RyR2 protein has multiple functional domains with specific roles, and four of these RyR2 protomers are required to form the quaterna...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/12/8/1030 |