Molecular, Subcellular, and Arrhythmogenic Mechanisms in Genetic RyR2 Disease

The ryanodine receptor (RyR2) has a critical role in controlling Ca<sup>2+</sup> release from the sarcoplasmic reticulum (SR) throughout the cardiac cycle. RyR2 protein has multiple functional domains with specific roles, and four of these RyR2 protomers are required to form the quaterna...

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Détails bibliographiques
Auteurs principaux: Ewan Douglas Fowler, Spyros Zissimopoulos
Format: Article
Langue:English
Publié: MDPI AG 2022-07-01
Collection:Biomolecules
Sujets:
Accès en ligne:https://www.mdpi.com/2218-273X/12/8/1030