Canine Mammary Tumours Are Affected by Frequent Copy Number Aberrations, including Amplification of MYC and Loss of PTEN.

Canine Mammary Tumours Are Affected by Frequent Copy Number Aberrations, including Amplification of MYC and Loss of PTEN.

<h4>Background</h4>Copy number aberrations frequently occur during the development of many cancers. Such events affect dosage of involved genes and may cause further genomic instability and progression of cancer. In this survey, canine SNP microarrays were used to study 117 canine mammar...

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Main Authors: Kaja S Borge, Silje Nord, Peter Van Loo, Ole C Lingjærde, Gjermund Gunnes, Grethe I G Alnæs, Hiroko K Solvang, Torben Lüders, Vessela N Kristensen, Anne-Lise Børresen-Dale, Frode Lingaas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126371

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https://doi.org/10.1371/journal.pone.0126371

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