Substituted N-Benzylpyrazine-2-carboxamides: Synthesis and Biological Evaluation

Substituted N-Benzylpyrazine-2-carboxamides: Synthesis and Biological Evaluation

A series of twelve amides was synthesized via aminolysis of substituted pyrazinecarboxylic acid chlorides with substituted benzylamines. Compounds were characterized with analytical data and assayed in vitro for their antimycobacterial, antifungal, antibacterial and photosynthesis-inhibiting activit...

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Bibliographic Details
Main Authors: Katarína Kráľová, Pavla Paterová, Matúš Peško, Vladimír Kubíček, Martin Doležal, Drahomíra Eibinová, Barbora Servusová
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Molecules
Subjects:
pyrazinamide analogues
lipophilicity determination
in vitro antimycobacterial
antifungal and photosynthesis inhibitory activity
Online Access:http://www.mdpi.com/1420-3049/17/11/13183

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http://www.mdpi.com/1420-3049/17/11/13183

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