Constitutional <i>BRCA1</i> and <i>MGMT</i> Methylation Are Significant Risk Factors for Triple-Negative Breast Cancer and High-Grade Serous Ovarian Cancer in Saudi Women

Constitutional <i>BRCA1</i> and <i>MGMT</i> Methylation Are Significant Risk Factors for Triple-Negative Breast Cancer and High-Grade Serous Ovarian Cancer in Saudi Women

Breast cancer (BC) and ovarian cancer (OC) are rapidly increasing in Saudi Arabia. <i>BRCA1</i> and <i>MGMT</i> epimutations have been linked to a higher risk of these malignancies. The present research investigated the impact of these epimutations on the prevalence of BC and...

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Bibliographic Details
Main Authors: Nisreen Al-Moghrabi, Maram Al-Showimi, Amal Alqahtani, Osama Almalik, Hamed Alhusaini, Ghdah Almalki, Ajawhara Saad, Elaf Alsunayi
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>BRCA1</i> methylation
<i>MGMT</i> methylation
breast cancer
TNBC
ovarian cancer
HGSOC
Online Access:https://www.mdpi.com/1422-0067/25/6/3108

Internet

https://www.mdpi.com/1422-0067/25/6/3108

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