The dark side of the moon: the immune-mediated adverse events of IL-17A/IL-17R inhibition

As aberrant IL-17 signaling plays a critical role in the pathogenesis of psoriasis, biologic agents targeting this pathway have become an important weapon against this disease. Some biologic agents such as IL-17 inhibitors (secukinumab and ixekizumab) and the IL-17 receptor (IL17R) inhibitor (brodal...

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Bibliographic Details
Main Authors: Francesco Messina, Stefano Piaserico
Format: Article
Language:English
Published: Taylor & Francis Group 2022-07-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:http://dx.doi.org/10.1080/09546634.2022.2062281