A novel multiplex PCR-RFLP method for simultaneous detection of the <it>MTHFR 677 C > T</it>, <it>eNOS +894 G > T</it> and <it>- eNOS -786 T > C</it> variants among Malaysian Malays

<p>Abstract</p> <p>Background</p> <p>Hyperhomocysteinemia as a consequence of the MTHFR 677 C > T variant is associated with cardiovascular disease and stroke. Another factor that can potentially contribute to these disorders is a depleted nitric oxide level, which c...

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Bibliographic Details
Main Authors: Loo Keat, Griffiths Lyn, Gan Siew
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/13/34