β-Sitosterol Attenuates Dexamethasone-Induced Muscle Atrophy via Regulating FoxO1-Dependent Signaling in C2C12 Cell and Mice Model

β-Sitosterol Attenuates Dexamethasone-Induced Muscle Atrophy via Regulating FoxO1-Dependent Signaling in C2C12 Cell and Mice Model

Sarcopenia refers to a decline in muscle mass and strength with age, causing significant impairment in the ability to carry out normal daily functions and increased risk of falls and fractures, eventually leading to loss of independence. Maintaining protein homeostasis is an important factor in prev...

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Bibliographic Details
Main Authors: Young-Sool Hah, Won Keong Lee, Sangyeob Lee, Eun Ji Kim, Jung Hyeon Lee, Seung-Jun Lee, Yeong Ho Ji, Sang Gon Kim, Hyeong-Hwan Lee, Seo Yeon Hong, Jun-Il Yoo
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Nutrients
Subjects:
β-sitosterol
FoxO1
dexamethasone
muscle atrophy
MuRF1
MAFbx
Online Access:https://www.mdpi.com/2072-6643/14/14/2894

Internet

https://www.mdpi.com/2072-6643/14/14/2894

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