Aberrant neuronal connectivity and network activity of neurons derived from patients with idiopathic schizophrenia

Aberrant neuronal connectivity and network activity of neurons derived from patients with idiopathic schizophrenia

Schizophrenia (SCZ) is a psychiatric disorder with a strong genetic determinant. A major hypothesis to explain disease aetiology comprises synaptic dysfunction associated with excitatory-inhibitory imbalance of synaptic transmission, ultimately contributing to impaired network oscillation and cognit...

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Bibliographic Details
Main Authors: Johanna Heider, Emilio Pardo González, Sophia-Marie Hartmann, Nirmal Kannaiyan, Sabrina Vogel, Richard Wüst, Andreas J. Fallgatter, Moritz J. Rossner, Udo Kraushaar, Hansjürgen Volkmer
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Neurobiology of Disease
Subjects:
Schizophrenia
E-I imbalance
iPSC
NGN2
AD2
Co-culture
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612400278X

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http://www.sciencedirect.com/science/article/pii/S096999612400278X

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