Conjugation Inhibitors Effectively Prevent Plasmid Transmission in Natural Environments

ABSTRACT Plasmid conjugation is a major route for the spread of antibiotic resistance genes. Inhibiting conjugation has been proposed as a feasible strategy to stop or delay the propagation of antibiotic resistance genes. Several compounds have been shown to be conjugation inhibitors in vitro, speci...

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Bibliographic Details
Main Authors: Carolina Palencia-Gándara, María Getino, Gabriel Moyano, Santiago Redondo, Raúl Fernández-López, Bruno González-Zorn, Fernando de la Cruz
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01277-21