Asymmetric Membrane Capsules for Extended Delivery of the Weakly Basic Drug Carvedilol

The objective of this study was to demonstrate that asymmetric membrane capsules can be used to deliver a poorly water soluble drug with a pH dependent solubility, such as carvedilol, for extended periods of time by modulating solubility with acid. In this study, the effect of the concentration of p...

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Bibliographic Details
Main Authors: Kumar Guarve, Ghanshyam Das Gupta
Format: Article
Language:English
Published: MDPI AG 2010-05-01
Series:Pharmaceutics
Subjects:
Online Access:http://www.mdpi.com/1999-4923/2/2/199/