TRPV1 Activation Promotes β-arrestin2 Interaction with the Ribosomal Biogenesis Machinery in the Nucleolus: Implications for p53 Regulation and Neurite Outgrowth

TRPV1 Activation Promotes β-arrestin2 Interaction with the Ribosomal Biogenesis Machinery in the Nucleolus: Implications for p53 Regulation and Neurite Outgrowth

Transient receptor potential vanilloids (TRPV1) are non-selective cation channels that sense and transduce inflammatory pain signals. We previously reported that activation of TRPV1 induced the translocation of β-arrestin2 (ARRB2) from the cytoplasm to the nucleus, raising questions about the functi...

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Bibliographic Details
Main Authors: Ahmed Hassan, Mircea Iftinca, Daniel Young, Robyn Flynn, Francina Agosti, Nasser Abdullah, Manon Defaye, Mark G. H. Scott, Antoine Dufour, Christophe Altier
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
TRPV1
β-arrestins
ribosomal biogenesis
neuroplasticity
chronic pain
Online Access:https://www.mdpi.com/1422-0067/22/5/2280

Internet

https://www.mdpi.com/1422-0067/22/5/2280

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