SOX11/PRDX2 axis modulates redox homeostasis and chemoresistance in aggressive mantle cell lymphoma

Abstract Mantle cell lymphoma (MCL) is an incurable B-cell neoplasm characterized by an aggressive behavior, short responses to conventional therapies and SOX11 overexpression, which is associated with aggressive disease features and inferior clinical outcome of patients. Oxidative stress is known t...

Full description

Bibliographic Details
Main Authors: Anna De Bolòs, Marta Sureda-Gómez, Maria Carreras-Caballé, Marta-Leonor Rodríguez, Guillem Clot, Silvia Beà, Eva Giné, Elias Campo, Patricia Balsas, Virginia Amador
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-58216-2