Immunogenicity, Safety, and Anti-Viral Efficacy of a Subunit SARS-CoV-2 Vaccine Candidate in Captive Black-Footed Ferrets (<i>Mustela nigripes</i>) and Their Susceptibility to Viral Challenge

Immunogenicity, Safety, and Anti-Viral Efficacy of a Subunit SARS-CoV-2 Vaccine Candidate in Captive Black-Footed Ferrets (<i>Mustela nigripes</i>) and Their Susceptibility to Viral Challenge

A preliminary vaccination trial against the emergent pathogen, SARS-CoV-2, was completed in captive black-footed ferrets (<i>Mustela nigripes;</i> BFF) to assess safety, immunogenicity, and anti-viral efficacy. Vaccination and boosting of 15 BFF with purified SARS-CoV-2 S1 subunit protei...

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Bibliographic Details
Main Authors: Ariel E. Leon, Della Garelle, Airn Hartwig, Elizabeth A. Falendysz, Hon S. Ip, Julia S. Lankton, Tyler N. Tretten, Terry R. Spraker, Richard Bowen, Tonie E. Rocke
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
SARS-CoV-2
black-footed ferrets
mustelids
vaccination
experimental challenge
Online Access:https://www.mdpi.com/1999-4915/14/10/2188

Internet

https://www.mdpi.com/1999-4915/14/10/2188

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