Histone methyltransferase SETD1A interacts with notch and promotes notch transactivation to augment ovarian cancer development
Abstract Background High expression of SETD1A, a histone methyltransferase that specifically methylates H3K4, acted as a key oncogene in several human cancers. However, the function and underlying molecular mechanism of SETD1A in ovarian cancer (OV) remain markedly unknown. Methods The expression of...
Main Authors: | Hongjuan Chai, Chunpeng Pan, Mingyang Zhang, Haizhong Huo, Haiyan Shan, Jugang Wu |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-01-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-023-10573-3 |
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