Synthesis and Characterization of Impurities of Barnidipine Hydrochloride, an Antihypertensive Drug Substance

Barnidipine hydrochloride is a long term dihydropyridine calcium channel blocker used for the treatment of hypertension. During the process development of barnidipine hydrochloride, four barnidipine impurities were detected by high-performance liquid chromatography (HPLC) with an ordinary column (Ag...

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Bibliographic Details
Main Authors: Zhi-Gang Cheng, Xu-Yong Dai, Li-Wei Li, Qiong Wan, Xiang Ma, Guang-Ya Xiang
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/1/1344