Fine particulate matter 2.5 induces susceptibility to Pseudomonas aeruginosa infection via expansion of PD-L1high neutrophils in mice

Fine particulate matter 2.5 induces susceptibility to Pseudomonas aeruginosa infection via expansion of PD-L1high neutrophils in mice

Abstract Background Exposure to PM2.5 has been implicated in a range of detrimental health effects, particularly affecting the respiratory system. However, the precise underlying mechanisms remain elusive. Methods To address this objective, we collected ambient PM2.5 and administered intranasal chal...

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Bibliographic Details
Main Authors: Li Luo, Manling Jiang, Ying Xiong, Anying Xiong, Lei Zhang, Dehong Wu, Yao Liu, Qin Ran, Jiliu Liu, Yi Zhang, Jiahuan Li, Xiang He, Junyi Wang, Guoping Li
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Respiratory Research
Subjects:
PM2.5
PD-L1high neutrophils
Phagocytic function
Pseudomonas aeruginosa
Infection
Online Access:https://doi.org/10.1186/s12931-023-02640-x

Internet

https://doi.org/10.1186/s12931-023-02640-x

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