Role of Sox9 in BPD and its effects on the Wnt/β-catenin pathway and AEC-II differentiation
Abstract The excessive activation of the Wnt/β-catenin signaling pathway is an important regulatory mechanism that underlies the excessive proliferation and impaired differentiation of type 2 alveolar epithelial cells (AEC-II) in bronchopulmonary dysplasia (BPD). Sox9 has been shown to be an importa...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2024-01-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01795-2 |