PI3K/AKT/mTOR pathway and its related molecules participate in PROK1 silence-induced anti-tumor effects on pancreatic cancer

PI3K/AKT/mTOR pathway and its related molecules participate in PROK1 silence-induced anti-tumor effects on pancreatic cancer

The PI3K/AKT/mTOR (phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin) pathway can be initiated by PROK1 (prokineticin 1), but its effect and mechanism of action in pancreatic carcinoma (PC) are not fully understood. In this study, we elucidated the roles of PROK1 and its r...

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Bibliographic Details
Main Authors: Wang Feng, Yan Xiaogang, Hua Yongqiang, Song Jianjun, Liu Di, Yang Chun, Peng Fei, Kang Fuping, Hui Yongfeng
Format: Article
Language:English
Published: De Gruyter 2023-04-01
Series:Open Life Sciences
Subjects:
pancreatic cancer
prok1
apoptosis
proliferation
pi3k/akt/mtor
Online Access:https://doi.org/10.1515/biol-2022-0538

Internet

https://doi.org/10.1515/biol-2022-0538

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