Candida albicans evades NK cell elimination via binding of Agglutinin-Like Sequence proteins to the checkpoint receptor TIGIT

Candida albicans evades NK cell elimination via binding of Agglutinin-Like Sequence proteins to the checkpoint receptor TIGIT

Natural killer cells have emerged as critical immune cells in the response to fungal infection. Here the authors identify how Candida albicans evades the natural killer cell response via expression of ligands that directly modify the natural killer cell response and can be therapeutically targeted t...

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Bibliographic Details
Main Authors: Yoav Charpak-Amikam, Tom Lapidus, Batya Isaacson, Alexandra Duev-Cohen, Tal Levinson, Adi Elbaz, Francesca Levi-Schaffer, Nir Osherov, Gilad Bachrach, Lois L. Hoyer, Maya Korem, Ronen Ben-Ami, Ofer Mandelboim
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30087-z

Internet

https://doi.org/10.1038/s41467-022-30087-z

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