Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase II Inhibits Hepatitis B Virus Replication from cccDNA via AMPK Activation and AKT/mTOR Suppression

Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase II Inhibits Hepatitis B Virus Replication from cccDNA via AMPK Activation and AKT/mTOR Suppression

Ca<sup>2+</sup>/calmodulin-dependent protein kinase II (CaMKII), which is involved in the calcium signaling pathway, is an important regulator of cancer cell proliferation, motility, growth, and metastasis. The effects of CaMKII on hepatitis B virus (HBV) replication have never been eval...

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Bibliographic Details
Main Authors: Jumi Kim, Hyeonjoong Kwon, Fadia Kalsoom, Muhammad Azhar Sajjad, Hyun Woong Lee, Jin Hong Lim, Jaesung Jung, Yong-Joon Chwae, Sun Park, Ho-Joon Shin, Kyongmin Kim
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Microorganisms
Subjects:
hepatitis B virus
HBV replication
hepatocellular carcinoma
CaMKII
AMPK
AKT/mTOR signaling pathway
Online Access:https://www.mdpi.com/2076-2607/10/3/498

Internet

https://www.mdpi.com/2076-2607/10/3/498

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