Administration of BAY 41-2272 prevents bladder dysfunction in nitric-oxide deficient rats

Administration of BAY 41-2272 prevents bladder dysfunction in nitric-oxide deficient rats

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ABSTRACT Objective: to evaluate the protective effects of BAY 41-2272, a soluble guanylate cyclase activator, on changes in cystometric parameters in rats deficient in nitric oxide (NO). Methods: Rats were divided into the following groups: (a) control; (b) DMSO; (c) L-NAME; (d) BAY 41-2272 alone;...

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Bibliographic Details
Main Authors: Carlos Arturo Levi D'Ancona, Fabíola Zakia Taufic Mónica, Ricardo Reges, David Cohen, Fabio Henrique da Silva, Gilberto De Nucci, Edson Antunes
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2010-12-01
Series:Einstein (São Paulo)
Subjects:
Guanylate cyclase
Nitric oxide
Urinary bladder, overactive
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082010000400404&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082010000400404&tlng=en

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