Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes

Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes

We analyzed the effects of the common BMI-increasing melanocortin 4 receptor (MC4R) rs17782313-C allele with a minor allele frequency of 0.22–0.25 on (1) cardiovascular disease outcomes in two large population-based cohorts (Copenhagen City Heart Study and Copenhagen General Population Study, <i&...

Full description

Bibliographic Details
Main Authors: Lisanne L. Blauw, Raymond Noordam, Sander W. van der Laan, Stella Trompet, Sander Kooijman, Diana van Heemst, Johan Wouter Jukema, Jessica van Setten, Gert J. de Borst, Anne Tybjærg-Hansen, Gerard Pasterkamp, Jimmy F. P. Berbée, Patrick C. N. Rensen
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Journal of Clinical Medicine
Subjects:
MC4R
genetics
cardiovascular disease
atherosclerosis
BMI
Online Access:https://www.mdpi.com/2077-0383/10/5/932

Internet

https://www.mdpi.com/2077-0383/10/5/932

Similar Items