The Quest for Anti-α-Synuclein Antibody Specificity—Lessons Learnt From Flow Cytometry Analysis

The Quest for Anti-α-Synuclein Antibody Specificity—Lessons Learnt From Flow Cytometry Analysis

The accumulation of alpha-synuclein (aSyn) is the hallmark of a group of neurodegenerative conditions termed synucleopathies. Physiological functions of aSyn, including those outside of the CNS, remain elusive. However, a reliable and reproducible evaluation of aSyn protein expression in different c...

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Bibliographic Details
Main Authors: Lukas Leupold, Veronika Sigutova, Elizaveta Gerasimova, Martin Regensburger, Sebastian Zundler, Friederike Zunke, Wei Xiang, Beate Winner, Iryna Prots
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Neurology
Subjects:
α-synuclein expression
antibody specificity
flow cytometry
antibodies
synuclein antibodies
alpha-synuclein
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.869103/full

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https://www.frontiersin.org/articles/10.3389/fneur.2022.869103/full

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