Role of BRAF in Hepatocellular Carcinoma: A Rationale for Future Targeted Cancer Therapies

The few therapeutic strategies for advance hepatocellular carcinoma (HCC) on poor knowledge of its biology. For several years, sorafenib, a tyrosine kinase inhibitors (TKI) inhibitor, has been the approved treatment option, to date, for advanced HCC patients. Its activity is the inhibition of the re...

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Bibliographic Details
Main Authors: Antonio Gnoni, Antonella Licchetta, Riccardo Memeo, Antonella Argentiero, Antonio G. Solimando, Vito Longo, Sabina Delcuratolo, Oronzo Brunetti
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1010-660X/55/12/754